Rate Control in Atrial Fibrillation



Status:Not yet recruiting
Conditions:Atrial Fibrillation
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:19 - Any
Updated:6/17/2016
Start Date:December 2016
End Date:September 2017
Contact:Caroline Nubel
Email:carolinenubel@creighton.edu
Phone:(402) 280-4032

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Trial Summary
Trial Overview
Inclusion Criteria

Rate Control in Atrial Fibrillation: A Randomized, Double-Blind, Crossover Comparison of Carvedilol and Metoprolol Tartrate

This study will evaluate the efficacy of metoprolol tartrate compared to carvedilol on heart
rate control in patients with atrial fibrillation and a rapid ventricular rate.


Inclusion Criteria:

- Permanent atrial fibrillation

- Baseline ventricular rate (prior to treatment) > 110 bpm

Exclusion Criteria:

- History of accessory tract re-entry tachycardia

- Ejection fraction < 35% or history of NYHA Class III/IV stage C/D heart failure

- Acute coronary syndrome, percutaneous coronary intervention, or cardiac surgery in
the past 2 months

- Child-Pugh class B or C hepatic dysfunction

- Uncontrolled hypertension

- Thyroid disease

- Intolerance to beta-blockers

- History of lung disease resulting in hospitalization in the past year
We found this trial at
1
site
Creighton University
2500 California Plaza
Omaha, Nebraska 68102
(402) 280-2700
Principal Investigator: Pallavi Bellamkonda, MBBS
Phone: 402-280-4032
Creighton University Creighton University, located in Omaha, Neb., offers a top-ranked education in the Jesuit...
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