DISCOVERY: A Study Examining the Prevalence of TTR Mutations in Subjects Suspected of Having Cardiac Amyloidosis



Status:Completed
Conditions:Cardiology, Hematology
Therapuetic Areas:Cardiology / Vascular Diseases, Hematology
Healthy:No
Age Range:18 - Any
Updated:7/21/2016
Start Date:June 2014
End Date:March 2016

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The purpose of this study is to characterize the frequency of TTR mutations in subjects
suspected of having cardiac amyloidosis


Inclusion Criteria:

- Males or females >18 years old

- History of evidence suggestive of cardiac amyloidosis

- Subject is willing and able to comply with protocol required assessments and provide
written informed consent

Exclusion Criteria:

- Known diagnosis of primary (AL) amyloidosis

- Known diagnosis of hereditary cardiomyopathy or cardiomyopathy due to aortic stenosis

- Patient is currently pregnant
We found this trial at
37
sites
Durham, North Carolina
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Anderlecht,
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Anderlecht,
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Athens, Georgia
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Athens, GA
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Atlanta, Georgia 30322
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Atlanta, GA
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Aurora, Colorado
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Bakersfield, California
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Baltimore, Maryland
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Boston, Massachusetts 02114
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Boston, MA
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Bronx, New York
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Bronx, NY
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Camden, New Jersey
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Camden, NJ
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Charleston, South Carolina
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Charleston, SC
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Chicago, Illinois 60153
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Chicago, IL
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Cleveland, Ohio 44195
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Cleveland, OH
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Detroit, Michigan
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Detroit, MI
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Falls Church, Virginia
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Falls Church, VA
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Fort Worth, Texas
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Fort Worth, TX
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Jackson, Mississippi
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Jackson, MS
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La Mesa, California
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La Mesa, CA
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Little Rock, Arkansas
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Little Rock, AR
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Los Angeles, California 90033
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Los Angeles, CA
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Macon, Georgia
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Macon, GA
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Merrillville, Indiana
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Merrillville, IN
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Norfolk, Virginia
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Norfolk, VA
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Philadelphia, Pennsylvania 19104
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Philadelphia, PA
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Pittsburgh, Pennsylvania
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Plano, Texas
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Plano, TX
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Richmond, Virginia
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Richmond, VA
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Rochester, New York
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Rochester, NY
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Rosedale, New York
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Rosedale, NY
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San Francisco, California
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San Francisco, CA
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Springfield, Massachusetts
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St. Louis, Missouri 63110
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Tampa, Florida
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Tampa, FL
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Torrance, California
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Washington, District of Columbia 20422
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Washington,
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Washington, District of Columbia 20422
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Washington,
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Williamsville, New York
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Williamsville, NY
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