Intravenous Lidocaine and Quality of Recovery After Cesarean Delivery
| Status: | Not yet recruiting |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | November 2014 |
| End Date: | July 2016 |
| Contact: | Jason R Farrer, M.D. |
| Email: | jfarrer@nmff.org |
| Phone: | 312-472-3585 |
The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Cesarean Delivery
When given intravenously, the local anesthetic lidocaine has been shown to decrease the
amount of pain medication patients require when recovering from several types of surgeries.
Cesarean delivery is a very common surgery in the United States, effecting more than 1
million women each year. The investigators hypothesize that lidocaine, given during and
immediately after a patient undergoes a cesarean section, will help improve a mother's
overall recovery experience, as well as positively influence bonding with her new baby.
amount of pain medication patients require when recovering from several types of surgeries.
Cesarean delivery is a very common surgery in the United States, effecting more than 1
million women each year. The investigators hypothesize that lidocaine, given during and
immediately after a patient undergoes a cesarean section, will help improve a mother's
overall recovery experience, as well as positively influence bonding with her new baby.
Pain after Cesarean delivery is a common occurrence on the labor and delivery unit. The
increased use of neuraxial anesthesia has allowed the administration of neuraxial opioids to
help with postoperative pain control. Many patients, however, still require IV and oral
opioids in the post anesthesia recovery unit (PACU), and on the postpartum nursing floor.
Post Cesarean delivery pain not only has the usual adverse effects common to all
postoperative pain (i.e. increased risk for deep vein thrombosis, pulmonary embolism,
coronary ischemia, pneumonia, poor wound healing, and psychological dysfunction) but also
has the potential to adversely affect mother-baby bonding, time spent in skin-to-skin
contact and success of initiating effective breastfeeding.
Systemic administration of lidocaine has been shown to decrease opioid consumption, improve
recovery of bowel function and promote a better recovery after inpatient procedures.
Lidocaine has been shown to have analgesic, antihyperalgesic and anti-inflammatory
properties. It also has an excellent safety profile when given by a low-dose infusion.
Assessing a patient's quality of recovery has become an important outcome in several
studies. The patient's capacity to return to her normal activities and effectively care for
her newborn is one of the most important signs of a successful surgical procedure, and it
has significant economic, sociological and psychological implications.
Quality of recovery -40(QoR-40) is a validated 40-item instrument to assess the quality of
post-operative recovery (10). Myles et al. have concluded that the QoR-40 would be a useful
outcome measure to assess the impact on changes in health care delivery, but anesthesia
studies underutilize this instrument.
This study will evaluate the effect of perioperative systemic lidocaine in the postoperative
quality of recovery of patients undergoing Cesarean delivery.
increased use of neuraxial anesthesia has allowed the administration of neuraxial opioids to
help with postoperative pain control. Many patients, however, still require IV and oral
opioids in the post anesthesia recovery unit (PACU), and on the postpartum nursing floor.
Post Cesarean delivery pain not only has the usual adverse effects common to all
postoperative pain (i.e. increased risk for deep vein thrombosis, pulmonary embolism,
coronary ischemia, pneumonia, poor wound healing, and psychological dysfunction) but also
has the potential to adversely affect mother-baby bonding, time spent in skin-to-skin
contact and success of initiating effective breastfeeding.
Systemic administration of lidocaine has been shown to decrease opioid consumption, improve
recovery of bowel function and promote a better recovery after inpatient procedures.
Lidocaine has been shown to have analgesic, antihyperalgesic and anti-inflammatory
properties. It also has an excellent safety profile when given by a low-dose infusion.
Assessing a patient's quality of recovery has become an important outcome in several
studies. The patient's capacity to return to her normal activities and effectively care for
her newborn is one of the most important signs of a successful surgical procedure, and it
has significant economic, sociological and psychological implications.
Quality of recovery -40(QoR-40) is a validated 40-item instrument to assess the quality of
post-operative recovery (10). Myles et al. have concluded that the QoR-40 would be a useful
outcome measure to assess the impact on changes in health care delivery, but anesthesia
studies underutilize this instrument.
This study will evaluate the effect of perioperative systemic lidocaine in the postoperative
quality of recovery of patients undergoing Cesarean delivery.
Inclusion Criteria:
- American Society of Anesthesiologists Class II
- English speaking
- Scheduled Cesarean delivery
Exclusion Criteria:
- Allergy to local anesthetics
- Chronic opioid use
- Greater than 2 prior cesarean deliveries
- Prior myomectomy
- Prior classical cesarean incision
- BMI greater than 40
- History of cardiac disease
We found this trial at
1
site
Click here to add this to my saved trials
