A Study To Evaluate The Difference In iPad-Based Cognitive Video Game (Akili Interactive's Project: EVO) Performance In Amyloid-Positive Versus Amyloid-Negative Healthy Elderly Volunteers
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 70 - 80 |
| Updated: | 7/27/2016 |
| Start Date: | September 2014 |
| End Date: | May 2016 |
A Randomized, Double Blind, Placebo Controlled Trial To Study Difference In Cognitive Learning Associated With Repeated Self-administration Of Remote Computer Tablet-based Application Assessing Dual-task Performance Based On Amyloid Status In Healthy Elderly Volunteers
The purpose of the study is to evaluate the difference in learning and performance measures
associated with repeated use of an iPad video game (Akili Interactive's Project: EVO) in
healthy elderly volunteers based on amyloid status.
associated with repeated use of an iPad video game (Akili Interactive's Project: EVO) in
healthy elderly volunteers based on amyloid status.
Inclusion Criteria:
- Healthy males and females between the ages of 70 and 80.
- Subjects must have BMI of 17.5 to 32 kg/m2 and total body weight > 110 pounds.
- Acceptable screening MRI and PET scans that pass quality control requirements.
Exclusion Criteria:
- Co-morbid diagnosis of clinically documented Alzheimer's disease; - Significant
cognitive impairment;
- MMSE (mini mental state examination) score <26
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