Postpartum Weight Loss and Exercise (PRIDE)



Status:Completed
Conditions:Endocrine, Diabetes
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 45
Updated:2/27/2019
Start Date:February 2011
End Date:December 2017

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Early Postpartum Treatment of Gestational Diabetes With Weight Loss and Exercise

The overall objective of this pilot project is to test in 50 women with a history of
gestational diabetes mellitus (GDM), the effectiveness and feasibility of an 8 month
intensive lifestyle intervention to reduce the rate of metabolic abnormalities within 1 year
after delivery.

The objective is in comparison to a group of women not enrolled in the lifestyle
intervention, 8 months of intensive lifestyle intervention aimed at promoting 7% weight loss
through increased physical activity and dietary modification in women with a history of GDM
will:

1. decrease body weight and

2. reduce the rate of metabolic abnormalities, 12 months after delivery

Inclusion Criteria:

- Women are required to be enrolled (provided written consent for participation) in the
COPSS-GDM study and therefore have met the following inclusion criteria:

- Postpartum Women ≥18 years to 45 years (inclusive) of age who experienced GDM
during index pregnancy

- English-speaking

Exclusion Criteria:

- Exclusion Criteria:

- Women enrolled in COPSS-GDM will be excluded if they met the following criteria:

Medical Exclusion Criteria

- History or clinical manifestation of any other significant metabolic, hematologic,
pulmonary, cardiovascular, gastrointestinal, neurologic, immune, hepatic, renal,
urologic disorders, or cancer

- Regular use of medications for weight control or psychosis

- Current use of medication to treat diabetes Psychiatric and Behavioral Exclusion
Criteria

- History or clinical manifestation of any eating disorder

- Smoking

- History of drug or alcohol abuse (up to 14 drinks a week are allowed) within the past
two years Other Exclusion Criteria

- Pregnancy or pregnancy planned during the coming year

- Unwilling or unable to adhere to the clinical evaluation schedule over the twelve
-month study period
We found this trial at
1
site
6400 Perkins Rd
Baton Rouge, Louisiana 70808
(225) 763-2500
Principal Investigator: Leanne M. Redman, RhD
Phone: 225-763-2759
Pennington Biomedical Research Center Unlike other medical research facilities where science occurs in separate labs...
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mi
from
Baton Rouge, LA
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