Diabetic Shoulder Mobility
| Status: | Completed |
|---|---|
| Conditions: | Diabetes |
| Therapuetic Areas: | Endocrinology |
| Healthy: | No |
| Age Range: | 40 - 70 |
| Updated: | 11/9/2017 |
| Start Date: | September 2014 |
| End Date: | October 12, 2016 |
Diabetic Upper Extremity Pathophysiology, Limited Joint Mobility and Disability
The primary goal of this project is to determine how advanced glycation end-product (AGEs)
accumulation and shoulder movement (humeral thoracic range of motion and "activity count")
interact to contribute to shoulder limited joint mobility (LJM), pain and disability, and if
an intervention consisting of a tailored dose of stretching and active shoulder movement can
reduce these problems in people with diabetes mellitus (DM). The investigators will focus on
the following measures that span health domains; Skin intrinsic fluorescence to measure AGEs;
Ultrasound to measure supraspinatus tendon thickness; 3 dimensional joint range of motion and
"activity counts" to measure shoulder movements; and the Disability of the Arm, Shoulder and
Hand (DASH) questionnaire to measure patient reported pain and disability. The investigators
will test the innovative hypothesis that metabolic and movement factors interact to cause
severe shoulder problems in people with DM and that an optimized shoulder movement
intervention can have an important impact on reducing the development of limited joint
mobility, pain and disability in this population.
accumulation and shoulder movement (humeral thoracic range of motion and "activity count")
interact to contribute to shoulder limited joint mobility (LJM), pain and disability, and if
an intervention consisting of a tailored dose of stretching and active shoulder movement can
reduce these problems in people with diabetes mellitus (DM). The investigators will focus on
the following measures that span health domains; Skin intrinsic fluorescence to measure AGEs;
Ultrasound to measure supraspinatus tendon thickness; 3 dimensional joint range of motion and
"activity counts" to measure shoulder movements; and the Disability of the Arm, Shoulder and
Hand (DASH) questionnaire to measure patient reported pain and disability. The investigators
will test the innovative hypothesis that metabolic and movement factors interact to cause
severe shoulder problems in people with DM and that an optimized shoulder movement
intervention can have an important impact on reducing the development of limited joint
mobility, pain and disability in this population.
Inclusion Criteria:
- individuals with type 2 DM and duration of diagnosed diabetes more than 10 years OR
type 2 DM and presence of a 'positive prayer sign' OR shoulder flexion < 150 degrees;
disability of arm, shoulder and hand (DASH) scores in the range of <70%; between the
age of 40-70 will be recruited.
Exclusion Criteria:
- currently diagnosed adhesive capsulitis
- diagnosed rotator cuff tear
- recent (6 months) upper extremity injury and/or fractures
- surgery in the upper extremity or thorax
- cervical radiculopathy
- thoracic outlet syndrome
- stroke with residual upper extremity involvement
- severe skin allergies in area to be tested
- rheumatic conditions
- known connective tissue diseases
- carpal tunnel syndrome
- use of a cane
- individuals who engage in heavy upper extremity/ overhead use (ie, painters, tennis
players) because they likely have a different mechanism of injury than those with low
shoulder activity.
We found this trial at
1
site
660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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