The Combination of Adductor Canal Block and Periarticular Injection. A Novel Technique for Patients Undergoing Total Knee Replacement (ACB PAI)

A total of 106 patients undergoing total knee arthroplasty will be randomized into two
groups: one to receive only Periarticular injections and the other periarticular injections
AND adductor canal block.

Patients will be asked their numeric pain scores before surgery as baseline and at 24 and 48
hours post-operation. Patients also will be asked questions from painOUT questionnaire at 24
and 48 hours.

Time to reach discharge criteria based on physical therapy assessments will also be measured.

Inclusion Criteria:

- Patients with osteoarthritis scheduled for primary tricompartmental total knee
arthroplasty with a participating surgeon

- Age 18 to 80 years

- Planned use of regional anesthesia

- Ability to follow study protocol

- English speaking (secondary outcomes include questionnaires validated in English only)

Exclusion Criteria:

Hepatic or renal insufficiency Patients younger than 18 years old and older than 80
Patients intending to receive general anesthesia Patients planning to go to rehab post
operatively Patients scheduled to go into the OR after 1 pm Allergy or intolerance to one
of the study medications Patients with an ASA of IV Chronic gabapentin/pregabalin use
(regular use for longer than 3 months) Chronic opioid use (taking opioids for longer than 3
months) Diabetes Patients on workers compensation or disability