Ocular Surface Microbiome
| Status: | Recruiting |
|---|---|
| Conditions: | Ocular |
| Therapuetic Areas: | Ophthalmology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | July 2013 |
| End Date: | June 2017 |
| Contact: | Sue Rath |
| Email: | raths@uw.edu |
| Phone: | 206-897-4331 |
Diversity and Dynamic Stability of the Ocular Surface Microbiome
The purpose of this study is to collect samples from the surface of eyelids to try to grow
and identify bacteria or fungus that might be present, and to try to understand why people
have dry eye symptoms.
and identify bacteria or fungus that might be present, and to try to understand why people
have dry eye symptoms.
"Dry eye" is a very common eye condition, which may or may not be caused by specific
microorganisms that live on the surface of the eye. In this study, a combination of tissue
culture and molecular biology techniques will be used to identify every microbe (bacteria,
fungus, or virus) on the surface of eyes of people with dry eye syndrome, as well as a
'control' group of people who don't have dry eye disease.
microorganisms that live on the surface of the eye. In this study, a combination of tissue
culture and molecular biology techniques will be used to identify every microbe (bacteria,
fungus, or virus) on the surface of eyes of people with dry eye syndrome, as well as a
'control' group of people who don't have dry eye disease.
Inclusion Criteria:
- Subjects with ocular surface discomfort with an Ocular Surface Disease Index score of
greater than 60
- Subjects with and Ocular Surface disease Index score less than 30
- Males and females age 18 or older
Exclusion Criteria:
- Contact lens wear
- Use of oral or topical antibiotics in past 6 months
- Use of prescription eye medication in past 6 months
- Penetrating ocular or keratoplasty surgery in last 12 months
- Children under the age of 18
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