Attention Bias Modification for Transdiagnostic Anxiety
| Status: | Completed |
|---|---|
| Conditions: | Anxiety |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 4/17/2018 |
| Start Date: | April 2013 |
| End Date: | January 2018 |
Neural Dimensions of Attention Bias Modification for Transdiagnostic Anxiety
This project seeks to identify neural mechanisms underlying the tendency for anxious
individuals to pay more attention to threatening information than to other types of
information. A computerized treatment designed to train individuals to reduce their attention
towards threat will be tested, with a focus on understanding the aspects of brain function
that predict response to the treatment. This work could ultimately lead to the ability to
treat anxiety more effectively by directly targeting the aspects of brain function that are
altered in a given patient.
individuals to pay more attention to threatening information than to other types of
information. A computerized treatment designed to train individuals to reduce their attention
towards threat will be tested, with a focus on understanding the aspects of brain function
that predict response to the treatment. This work could ultimately lead to the ability to
treat anxiety more effectively by directly targeting the aspects of brain function that are
altered in a given patient.
Inclusion Criteria:
- Participants will:
1. be between the ages of 18 and 55 years,
2. score >45 on the Spielberger State-Trait Anxiety Inventory—trait form.
3. score >=75th percentile on the World Health Organization Disability Assessment
Schedule 2.0
Exclusion Criteria:
1. Current medication or Cognitive-Behavioral Therapy for anxiety or depression;
2. Failure to meet standard Magnetic Resonance Imaging (MRI) inclusion criteria: those
who have cardiac pacemakers, neural pacemakers, surgical clips in the brain or blood
vessels, surgically implanted metal plates, screws or pins, cochlear implants,
Intrauterine Devices, metal braces, or other metal objects in their body, especially
in the eye. If the subject has any metal or implants in the body they must be deemed
safe by the MRI Research Center's safety screening procedure prior to enrollment.
Dental fillings do not present a problem. Plastic or removable dental appliances do
not require exclusion. Pregnancy, determined by pregnancy tests on females.
3. currently suicidal or at risk for harm to self or others,
4. visual disturbance (<20/40 as per the Snellen test, corrective lenses allowed)
5. <6th grade reading level as per the Wide Range Achievement Test
6. presence of bipolar, psychotic, autism spectrum, substance dependence, or primary
depressive disorder
7. positive urine drug test
We found this trial at
1
site
Pittsburgh, Pennsylvania 15213
Phone: 412-383-5443
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