Multipolar Mapping and Atrial Arrhythmias



Status:Completed
Conditions:Atrial Fibrillation, Atrial Fibrillation
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:45 - Any
Updated:4/21/2016
Start Date:November 2014
End Date:December 2015

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Atrial Signal Analysis Using a Multipolar Catheter in Patients Undergoing Atrial Fibrillation and Flutter Ablations

This clinical investigation utilizes the Constellation Full Contact Mapping catheter in the
left and right atria to explore atrial signal characteristics that can guide atrial
fibrillation and atrial flutter ablation procedures more effectively.

Atrial fibrillation (AF) and atrial flutter (AFL) are the most common cardiac arrhythmias in
adults, and account for a substantial portion of patient morbidity and healthcare
expenditures. Great effort has been put forth to discover effective treatments for AF/FL.
Promising results of catheter ablation suggest that AF/FL may be eliminated in a majority of
patients. For example, data from numerous laboratories shows that up to 85 percent of
patients with the paroxysmal form of AF may be free of recurrences and off anti-arrhythmic
drugs at one year follow-up.

Inclusion Criteria:

Patients referred to the PI (Dr. Biviano) or co-investigators in the Program of Cardiac
Electrophysiology at Columbia University Medical Center who are scheduled to undergo
ablation will be approached for recruitment:

- Older than 45 years of age

- History of AF and/or AFL and are candidates for catheter ablation.

Exclusion Criteria:

Patients not fitting the above clinical criteria or unwilling to comply with the
instructions of the monitor are excluded, as well as patients with the following:

- Permanent leads or prosthetic or stenotic valves present

- Active systemic infection

- Echocardiographically-confirmed visual presence of thrombus

- For whom the inability of obtaining vascular access exists

- Heparin-induced thrombocytopenia

- Hemodynamic instability or shock
We found this trial at
1
site
630 W 168th St
New York, New York
212-305-2862
Columbia University Medical Center Situated on a 20-acre campus in Northern Manhattan and accounting for...
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mi
from
New York, NY
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