A New Method for Detection of Bacteria in the Bloodstream
| Status: | Recruiting |
|---|---|
| Conditions: | Other Indications |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/16/2019 |
| Start Date: | January 2015 |
| End Date: | March 2020 |
| Contact: | Tera Thigpin |
| Email: | Tera.thigpin@surgery.ufl.edu |
| Phone: | (352) 273-5670 |
The primary aim is to determine if this new technique will detect and identify bacteria in
the blood sooner than standard blood cultures or identify patients who may be septic without
growing bacteria in their cultures. These will be correlated with the data collected from
medical records on presumed sepsis. These results will be linked to data concerning infection
that will be available as part of routine care including blood counts and other laboratory
values that would be part of the routine medical care such as a white blood cell count. The
earlier the bacteria are identified and the appropriate antimicrobials are administered the
better the patient outcome.
the blood sooner than standard blood cultures or identify patients who may be septic without
growing bacteria in their cultures. These will be correlated with the data collected from
medical records on presumed sepsis. These results will be linked to data concerning infection
that will be available as part of routine care including blood counts and other laboratory
values that would be part of the routine medical care such as a white blood cell count. The
earlier the bacteria are identified and the appropriate antimicrobials are administered the
better the patient outcome.
This study will involve additional blood samples to be taken during the routine clinical
blood draw, while the subject is being treated for their burn/wounds. The additional research
samples will be examined for bacteria. A second blood draw will be performed at approximately
24 hours of initial blood collection. The blood is being collected and then correlate with
results of routine medical care blood cultures and clinical status of the subject (diagnosis
of sepsis, hemodynamic instability). Data that will be abstracted from the current electronic
medical record includes whether there is any type of catheter indwelling (brand name and
type), insertion methods including place of insertion (Intensive Care Unit, Operating Room,
Emergency Department), adherence to bundle, complications during insertion, colonization of
the subject with bacteria (MRSA), and culture results obtained as part of clinical care.
Demographics (subject's age) and diagnoses will also be captured as some studies have shown a
higher risk of infection with certain processes (burns) and percentage of burn.
blood draw, while the subject is being treated for their burn/wounds. The additional research
samples will be examined for bacteria. A second blood draw will be performed at approximately
24 hours of initial blood collection. The blood is being collected and then correlate with
results of routine medical care blood cultures and clinical status of the subject (diagnosis
of sepsis, hemodynamic instability). Data that will be abstracted from the current electronic
medical record includes whether there is any type of catheter indwelling (brand name and
type), insertion methods including place of insertion (Intensive Care Unit, Operating Room,
Emergency Department), adherence to bundle, complications during insertion, colonization of
the subject with bacteria (MRSA), and culture results obtained as part of clinical care.
Demographics (subject's age) and diagnoses will also be captured as some studies have shown a
higher risk of infection with certain processes (burns) and percentage of burn.
Inclusion Criteria:
- Burn patient with ≥20 % total body surface area burns or non-burned wound care patient
requiring wound care in the Burn Intensive Care Unit.
- Must weigh ≥ 50 kilograms
Exclusion Criteria:
- Pregnant or Lactating women
- Prisoners
We found this trial at
1
site
Gainesville, Florida 32610
Phone: 352-273-8630
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