Lean Body Mass Response to Higher-protein Diets During Winter Military Training



Status:Completed
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - Any
Updated:3/16/2015
Start Date:January 2015
End Date:February 2015
Contact:Stefan M Pasiakos, PhD
Email:stefan.pasiakos@us.army.mil
Phone:508-233-6474

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Effects of Carbohydrate and Protein Supplementation on Whole-body Protein Balance and Skeletal Muscle Mass During Winter Military Training: a Randomized Controlled Trial

The objectives of this study are to: 1) determine effects of a prototype recovery food
product providing supplemental energy on whole-body protein balance, skeletal muscle mass,
and biomarkers of physiological status and strain during winter military training, and 2)
determine the extent to which varying macronutrient composition (protein-based [PRO] versus
carbohydrate-based [CHO]) of the food product modulates the physiological consequences to
strenuous military training.

Up to 120 Norwegian Soldiers from the 2nd Battalion, Brigade North, Norwegian Army stationed
at Skjold Garrison will be enrolled in a 9-day, randomized controlled study. Using dietary
analysis, body composition assessments, stable isotope methodologies, basic biochemical
techniques, and measures of physiological strain, the effects of supplemental energy in the
form of carbohydrate and protein on indices of muscle mass and physiological status will be
assessed.

We hypothesize that consuming supplemental energy will attenuate the effects of severe
energy deficit on inflammation, androgenic hormones, and whole-body protein retention,
thereby protecting skeletal muscle mass. We expect that consuming PRO will promote a more
favorable recovery than consuming CHO, as indicated by measures of increased whole-body
protein synthesis and greater conservation of skeletal muscle mass.

Inclusion Criteria:

- Male and female Norwegian Soldiers aged 18 years or older participating in the 4-day
training program.

Exclusion Criteria:

- History of skin irritation (e.g., nickel or adhesive allergy), difficulty swallowing
large pills, and allergies to dairy products
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