Prospective Study of Colon Serrated Polyps
| Status: | Recruiting |
|---|---|
| Conditions: | Colorectal Cancer, Gastrointestinal |
| Therapuetic Areas: | Gastroenterology, Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/27/2018 |
| Start Date: | November 2014 |
| End Date: | November 2026 |
| Contact: | Gottumukkala S. Raju, MD |
| Phone: | 713-563-4377 |
With this study, the investigators plan to review the clinical, epidemiology, pathology, and
endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of
these lesions. The findings will help us define the natural history of colon serrated
lesions, develop techniques for endoscopic management of patients with serrated lesions, and
identity areas for improvement. The data will be used for continuing quality improvement and
presenting our outcomes at academic meetings and publishing our results in peer reviewed
journals.
endoscopic features of colon serrated lesions as well as outcome of endoscopic resection of
these lesions. The findings will help us define the natural history of colon serrated
lesions, develop techniques for endoscopic management of patients with serrated lesions, and
identity areas for improvement. The data will be used for continuing quality improvement and
presenting our outcomes at academic meetings and publishing our results in peer reviewed
journals.
Our goal is to collect data from our endoscopy reports and electronic medical record system
to complete a descriptive analysis of the demographics, colonoscopy resection procedure, and
outcome of resection - immediate and delayed complications, tumor recurrence, and cancer
during follow-up 010/01/2014 - 12/31/2025.
Specific variable to be reviewed:
1. Patient Demographics: Age, Sex, Race, Height, Weight, BMI (patient privacy will be
acknowledged).
2. Indications for Colonoscopy (screening, surveillance, symptoms or tertiary referral
[EMR]).
3. Comorbid conditions: cancer and surgical history, medical conditions.
4. Colonoscopy procedure: Quality of colon preparation (using the Boston Bowel Preparation
Scale) 0 - 3 for each section of the colon (Ascending, Transverse, Descending and Total
Colon), cecal intubation rate, cecal intubation and total procedure time, type of
colonoscope (if CO2 was used in the procedure and techniques for colonoscope insertion,
including position changes.
5. Examination findings: Number of polyps and nature of polyps removed (site, size,
surface, vascular pattern); type of polyp removed (serrated and sessile (flat); optical
features and histology of polyps.
6. Resection techniques: Biopsy, snare resection, endoscopic mucosal resection, endoscopic
submucosal dissection etc.
7. Including Pathology report findings so that a comparison can be made of the optical
features and actual pathology report.
8. Outcomes of colonoscopy: Complete or incomplete resection, local recurrence, need for
surgery, etc.
9. Outcome of colonoscopy: Complications (Bleeding and perforation).
to complete a descriptive analysis of the demographics, colonoscopy resection procedure, and
outcome of resection - immediate and delayed complications, tumor recurrence, and cancer
during follow-up 010/01/2014 - 12/31/2025.
Specific variable to be reviewed:
1. Patient Demographics: Age, Sex, Race, Height, Weight, BMI (patient privacy will be
acknowledged).
2. Indications for Colonoscopy (screening, surveillance, symptoms or tertiary referral
[EMR]).
3. Comorbid conditions: cancer and surgical history, medical conditions.
4. Colonoscopy procedure: Quality of colon preparation (using the Boston Bowel Preparation
Scale) 0 - 3 for each section of the colon (Ascending, Transverse, Descending and Total
Colon), cecal intubation rate, cecal intubation and total procedure time, type of
colonoscope (if CO2 was used in the procedure and techniques for colonoscope insertion,
including position changes.
5. Examination findings: Number of polyps and nature of polyps removed (site, size,
surface, vascular pattern); type of polyp removed (serrated and sessile (flat); optical
features and histology of polyps.
6. Resection techniques: Biopsy, snare resection, endoscopic mucosal resection, endoscopic
submucosal dissection etc.
7. Including Pathology report findings so that a comparison can be made of the optical
features and actual pathology report.
8. Outcomes of colonoscopy: Complete or incomplete resection, local recurrence, need for
surgery, etc.
9. Outcome of colonoscopy: Complications (Bleeding and perforation).
Inclusion Criteria:
1. All Patients with a serrated polyp (Hyperplastic polyps above sigmoid colon, sessile
serrated adenoma, traditional serrated adenoma)
Exclusion Criteria:
We found this trial at
1
site
1515 Holcombe Blvd
Houston, Texas 77030
Houston, Texas 77030
713-792-2121
Phone: 877-632-6789
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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