KV-CBCT and Ultrasound Imaging in Guiding Radiation Therapy in Patients With Prostate, Liver, or Pancreatic Cancer
| Status: | Recruiting |
|---|---|
| Conditions: | Prostate Cancer, Liver Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 19 - Any |
| Updated: | 4/4/2019 |
| Start Date: | September 22, 2015 |
| End Date: | December 2019 |
Integrated 3D X-ray and Ultrasound Guided Radiation Therapy of Soft Tissue Targets
This clinical trial studies if kilo-voltage cone beam computed tomography (KV-CBCT) and
ultrasound imaging works in guiding radiation therapy in patients with prostate, liver, or
pancreatic cancer. Computer systems, such as KV-CBCT and ultrasound imaging, allow doctors to
create a 3-dimensional picture of the tumor may help in planning radiation therapy and may
result in more tumor cells being killed.
ultrasound imaging works in guiding radiation therapy in patients with prostate, liver, or
pancreatic cancer. Computer systems, such as KV-CBCT and ultrasound imaging, allow doctors to
create a 3-dimensional picture of the tumor may help in planning radiation therapy and may
result in more tumor cells being killed.
PRIMARY OBJECTIVES:
I. To investigate the feasibility of combining on-board cone beam computed tomography (CBCT)
with ultrasound imaging to overcome the shortcomings of CBCT or ultrasound imaging alone for
imaging guided radiotherapy delivery.
OUTLINE:
Patients undergo ultrasound imaging prior to and during radiation therapy. Patients also
undergo kilo-voltage cone beam computed tomography prior to radiation therapy.
I. To investigate the feasibility of combining on-board cone beam computed tomography (CBCT)
with ultrasound imaging to overcome the shortcomings of CBCT or ultrasound imaging alone for
imaging guided radiotherapy delivery.
OUTLINE:
Patients undergo ultrasound imaging prior to and during radiation therapy. Patients also
undergo kilo-voltage cone beam computed tomography prior to radiation therapy.
Inclusion Criteria:
- The patient must have either 1) cancer involving the liver by biopsy or radiographic
criteria, or 2) prostate cancer by biopsy, with the intent of undergoing definitive
dose radiation therapy to targets within the liver, or prostate. Patients with
prostatectomy receiving post-operative radiotherapy are also eligible.
- Karnofsky performance status (PS) ≥ 70
- Subjects must have the ability to understand and the willingness to sign a written
informational form
Exclusion Criteria:
- Patients with uncontrolled inter-current illness or psychiatric illness/social
situations that would limit compliance with study requirements
We found this trial at
1
site
Cleveland, Ohio 44195
Principal Investigator: Ping Xia
Phone: 216-444-1938
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