Nasal Saline Irrigation After Radiation Therapy for Oropharyngeal Cancer

In this study, subjects are randomized to one of two study arms. They are either randomized
to receive nasal saline irrigation treatment (treatment group) or not to receive any nasal
irrigation treatment (control group). Subjects randomized to the treatment group will be
provided with saline packets to mix with water. All study subjects will be asked to complete
questionnaires during the study. If a subject completes all study related activities, their
total length of participation in the study will last about 2 months.

Inclusion Criteria:

- All patients seen in the KUMC Ear, Nose and Throat clinic with oropharyngeal cancer
that have undergone radiation therapy as the primary treatment

Exclusion Criteria:

- Patients that are at high risk for infection secondary to nasal irrigation

- Patients with autoimmune disease or immune deficiency