Neuronal and Behavioral Effects of Implicit Priming in Obese Individuals



Status:Recruiting
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:21 - 65
Updated:2/1/2019
Start Date:May 2013
End Date:December 2019
Contact:Jason R Tregellas, PhD
Email:jason.tregellas@ucdenver.edu
Phone:303-724-6232

Use our guide to learn which trials are right for you!

The overall goals of this project are to determine the impact of an implicit priming
intervention, designed to alter food perceptions, on both brain responses to food and on food
intake behaviors in overweight/obese individuals. The investigators hypothesized that this
bottom-up sensory-level conditioning approach would effectively result in reduced preference
for high-calorie foods.

One factor that may contribute to susceptibility to obesity is a high responsivity to
high-calorie foods in terms of cognitive factors such as emotional associations, reward value
or reinforcing properties of food. Many of these processes involve learned associations
thought to develop via classical conditioning through repeated pairings with external
stimuli, which can influence food preferences and intake. As such, improving our
understanding of the neuronal mechanisms underlying these processes and attempting to modify
them may be a useful strategy to promote weight loss and maintenance. Therefore, the proposed
study aims to investigate the effects of altering food perception on neuronal responses and
food intake behaviors by using implicit priming, in which positively or negatively valenced
images are presented immediately prior to food images, but are not consciously perceived.

The project goals are to determine the impact of the implicit priming intervention on both
brain responses to food cues and on food intake behaviors in overweight/obese individuals.
Food image ratings and neuronal responses to visual food cues will be assessed before and
after either (a) an active implicit priming intervention or (b) a control intervention.
Following fMRI, food intake will be measured.

Inclusion Criteria:

- Overweight/obese adults

- Healthy weight adults

Exclusion Criteria:

- Vegetarian, vegan, or having other wide-ranging food restrictions

- Currently dieting
We found this trial at
1
site
13001 E 17th Pl
Aurora, Colorado 80045
(303) 724-5000
Phone: 303-724-5809
University of Colorado Anschutz Medical Campus Located in the Denver metro area near the Rocky...
?
mi
from
Aurora, CO
Click here to add this to my saved trials