18F-AV-1451 High Resolution Autopsy Study



Status:Completed
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:60 - 89
Updated:10/26/2018
Start Date:June 2015
End Date:May 18, 2018

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A High Resolution Autopsy Study Evaluating the Relationship of 18F-AV-1451 PET Imaging and Tau Pathology

The study is designed to examine the relationship between imaging results detected on a
18F-AV-1451 PET scan and pathology found at autopsy within six months of imaging.


Inclusion Criteria:

- Projected life expectancy ≤ 6 months

Exclusion Criteria:

- Primary brain tumor, known metastases to the brain, central nervous system lymphoma

- Major, focal structural brain lesion

- Aggressively being treated with life sustaining measures

- Clinically significant infectious disease

- History of risk factors for Torsades de Pointes or are currently taking medication
known to cause QT prolongation

- Have received or participated in a trial with investigational medications in the past
30 days

- Females of childbearing potential who are pregnant or not using adequate contraception
We found this trial at
2
sites
San Francisco, California 94143
Principal Investigator: Duygu Tosun-Turgut
Phone: 415-221-4810
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Phoenix, Arizona 85006
Principal Investigator: Allison Perrin, MD
Phone: 602-839-6900
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Phoenix, AZ
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