A Phase 2b Study of CSL112 in Subjects With Acute Myocardial Infarction.

Inclusion Criteria:

- Men or women, at least 18 years of age, with evidence of myocardial necrosis in a
clinical setting consistent with a type I (spontaneous) acute myocardial infarction
(AMI), in the last week.

Exclusion Criteria:

- Ongoing hemodynamic instability

- Evidence of hepatobiliary disease

- Evidence of chronic kidney disease (CKD) (Stage III, IV, or V), defined as moderate
or severe renal impairment or if subject is receiving dialysis

- Evidence of unstable renal function

- History of acute kidney injury after previous exposure to an intravenous contrast
agent.

- Known history of allergies, hypersensitivity or deficiencies to CSL112 or any of its
components

- Other severe comorbid condition, concurrent medication, or other issue that renders
the subject unsuitable for participation in the study