Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy



Status:Completed
Conditions:Post-Surgical Pain
Therapuetic Areas:Musculoskeletal
Healthy:No
Age Range:18 - 80
Updated:4/17/2018
Start Date:June 2015
End Date:January 2017

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Administration of Pre-Operative Gabapentin to Patients Undergoing Laparoscopy: A Prospective Double-blinded, Placebo Controlled Randomized Study

The purpose of this study is to prospectively determine the influence of immediate
pre-operative gabapentin administration on acute postoperative pain. The investigators
hypothesize that immediate post-operative pain will be improved with pre-operative
administration of gabapentin.

The purpose of this study is to prospectively determine the influence of immediate
pre-operative gabapentin administration on acute postoperative pain. We hypothesize that
immediate post-operative pain will be improved with pre-operative administration of
gabapentin.

We plan to conduct a prospective randomized trial to assess the effect of a single immediate
pre-operative dose of gabapentin 300mg on immediate post-operative pain in patients
undergoing laparoscopy for gynecologic indications. This concept has been studied in patients
undergoing abdominal hysterectomy. We aim to study the effect on patients undergoing
laparoscopy.

Inclusion Criteria:

1. The patient must be female and planning to have a laparoscopic or robotic assisted
procedure for benign gynecologic indications.

2. Patients must be treated in the department of Obstetrics and Gynecology in the
division of Minimally Invasive Gynecologic Surgery.

3. The patient must be in the age range of 18-80 years, in general good health and able
to comply with study procedures.

Exclusion Criteria:

1. Male patients will be excluded from this study.

2. Patients under 18 years old will be excluded from this study.

3. Pregnant patients. All patients will have a routine pre-operative urine HCG to exclude
pregnancy.

4. Patients having abdominal, vaginal or hysteroscopic procedures

5. Allergy to gabapentin

6. Chronic use of gabapentin (greater than 6 months)
We found this trial at
1
site
Hershey, Pennsylvania 17033
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mi
from
Hershey, PA
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