Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies, Endocrine |
| Therapuetic Areas: | Endocrinology, Reproductive |
| Healthy: | No |
| Age Range: | 2 - Any |
| Updated: | 1/31/2018 |
| Start Date: | March 2014 |
| End Date: | August 2016 |
The purpose of this study is to determine presence of central adrenal insufficiency in
children with Prader Willi Syndrome using low dose (1 mcg) ACTH stimulation test compared to
results of overnight metyrapone test.
children with Prader Willi Syndrome using low dose (1 mcg) ACTH stimulation test compared to
results of overnight metyrapone test.
Inclusion Criteria:
- Individuals with Prader Willi Syndrome ages 2 years and older
Exclusion Criteria:
- Individuals who are ill at the time of study
- Individuals who are pregnant at the time of study
- Individuals who it is deemed unsafe to stop taking medications known to affect the
results of they study (hydrocortisone, phenytoin, estrogen, acetaminophen, oral
anti-diabetic agents).
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