Questionnaires in Identifying Upper Extremity Function and Quality of Life After Treatment in Patients With Breast Cancer

PRIMARY OBJECTIVES:

I. To characterize patients' upper extremity functionality (using the Disabilities of the
Arm, Shoulder and Hand [DASH] questionnaire) and their perception of quality of life (using
the Functional Assessment of Cancer Therapy-Breast [FACT-B] questionnaire) one to ten years
after breast cancer surgery and compare it to the general population.

II. To investigate whether patients' upper extremity functionality and their perception of
quality of life after completion of breast cancer treatment changes over the duration of
time between 1 -10 years after breast cancer surgery.

III. To characterize patient perception of the impact of breast cancer on their quality of
life in relation to current upper-extremity functionality 1-10 years after breast cancer
surgery.

IV. To characterize patients' upper extremity functionality (using the DASH questionnaire)
and their perception of the impact of breast cancer on their quality of life (using the
FACT-B questionnaire) in a sub group of individuals with stable metastatic breast cancer
1-10 years after initial diagnosis and surgery.

SECONDARY OBJECTIVES:

I. To assist the multidisciplinary team to identify musculoskeletal barriers (if any) that
impact a patient's long-term recovery with respect to the breast cancer treatments they have
received.

II. To assist in developing and implementing a physical therapy component within the
Personalized Medicine to Breast Cancer Care Plan; this includes early detection of potential
physical barriers, physical therapy intervention models, and development of survivorship
planning for cancer-related musculoskeletal impairments.

OUTLINE:

Patients complete the DASH and FACT-B questionnaires over 30-45 minutes.

Inclusion Criteria:

- All patients with a history of breast cancer surgery either lumpectomy, mastectomy,
axillary node dissection or sentinel node biopsy at least one year ago and received
either radiation therapy or chemotherapy or both

- Patients with no active disease; (as defined as no detectable disease)

- Patients with stable metastatic disease which is defined as (metastatic tumor
demonstrates no increase in volume, tumor size or diameter and no evidence of new
lesions, have been identified during last assessment by medical
oncologist/radiologist or surgeons)

- Signed informed consent

Exclusion Criteria:

- Survivors of breast cancer that have not received either breast surgery or radiation
therapy

- Patients with known cognitive impairments

- Individuals with progressive metastatic disease in which the tumor has increased in
size, volume and diameter or evidence of new lesions, as noted by medical
oncologists, radiologists and surgeons

- individuals who are non-ambulatory

- Women who self-report to be pregnant

- As this is an observational study, we will not be performing a pregnancy test,
participants will be asked if they are or are not pregnant