Acute Effects of Nutrition Supplementation on Treatment Efficiency and Hemodynamics During Dialysis

The consumption of food or nutritional supplements during hemodialysis treatment has been
shown to improve nutritional status, improve quality of life, and reduce mortality.

Despite these observations, allowing patients to eat food during hemodialysis treatment is
sometimes restricted in the United States. The reasons for this restrictive policy are
multi-factorial, but include concerns related to drops in blood pressure BP or a reduced
efficiency of solute removal following eating during HD treatment. An alternative to eating
solid food is to provide patients with liquid nutritional supplements. Clinics in the US are
more likely to allow the consumption of liquid nutritional supplements, however, little is
known about the effect that liquid supplements have on blood pressure or treatment
efficiency. Therefore, the investigators plan to examine the effect of nutritional
supplementation during hemodialysis treatment on hemodynamics and treatment efficiency in a
crossover design.

Inclusion Criteria:

- Receiving hemodialysis treatment three times per week, on hemodialysis for greater
than three months, receive medical clearance from a Nephrologists

Exclusion Criteria:

- Milk or soy allergy, more than 4 hypotensive events requiring intervention in the last
two weeks, hospitalized due to hypotension in the previous week