dHACM in Lumbar Decompression and Microdiscectomy Surgery

Inclusion Criteria:

- Patients over 18 years of age

- Patients with single- or multi-level spinal stenosis undergoing open lumbar
laminectomy or

- Patients with single-level herniated nucleus pulposus undergoing single-level lumbar
microdiscectomy

- Ability to provide full written consent

Exclusion Criteria:

- Patients under the age 18 years of age

- Non-English speaking patients

- Non-surgical candidate defined as any patient deemed by the surgeon not to be a
surgical candidate cannot participate for the following reasons: that patient does
not meet indications for lumbar laminectomy or microdiscectomy surgery, patient has a
contraindication to surgery such as medical comorbidities, pregnancy, etc.

- Patient allergic to aminoglycosides

- Is a prisoner

- Is involved in worker's compensation or other litigation relative to the spine injury

- Has a history of drug or alcohol abuse within the last 12 months

- Is currently participating in another drug or device clinical trial

- Previous spinal surgery

- Patients with history of deformity, mechanical instability, or spinal fusion
requirement

- History of hard- or soft-tissue spinal infection

- Has signs or symptoms of any disease, such as autoimmune disease, which could result
in allograft failure, or has experienced allograft failure in the past

- Patients unable to undergo an MRI

- Patients unwilling or unable to return for routine follow-up or complete outcome
instruments at the specified timepoints pre-and post-operatively