Cognitive Training and Practice Effects in MCI

The current study will test the effectiveness of a computerized cognitive (thinking) training
program on improving thinking and memory in patients with mild cognitive impairment. The
investigators will also examine how short term changes in thinking abilities (i.e., practice
effects) can be related to improvement in thinking abilities after the cognitive training
program.

Inclusion Criteria:

- Mild Cognitive Impairment, amnestic subtype

- 65 years of age or older

- Availability of a knowledgeable informant

- Access to internet 3 hours per week

- Adequate vision, hearing, and motor responding to participate in training

Exclusion Criteria:

- History of major stroke, head injury with loss of consciousness of >30 minutes, or
other neurological disorder or systemic illness that are thought to be affecting
cognition (e.g., seizure disorder, demyelinating disorder, etc.)

- Current or past major psychiatric illness (e.g., schizophrenia, bipolar affective
disorder)

- History of substance abuse

- Current use of antipsychotics or anticonvulsant medications

- Currently residing in a nursing home or other skilled nursing facility