A Novel Neurorehabilitation Approach for Cognitive Aging With HIV
| Status: | Completed |
|---|---|
| Conditions: | Healthy Studies, HIV / AIDS |
| Therapuetic Areas: | Immunology / Infectious Diseases, Other |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 4/21/2016 |
| Start Date: | March 2015 |
| End Date: | January 2016 |
Speed of Processing Training With Transcranial Direct Current Stimulation in Older HIV+ Adults (HtDCS)
The goal of this study is to conduct a small, self-contained project to test the hypothesis
that tDCS will augment SOP cognitive remediation therapy (CRT) in older HIV+ adults. The
investigators will randomly assign 60 HIV+ older adults (i.e., ≥ 50 years old) to 10-hours
in either a SOP CRT + sham tDCS condition (n=30) or SOP CRT + active tDCS condition (n=30)
and examine neurocognitive functioning at baseline and 6 weeks post-intervention. Hypothesis
1: The SOP CRT + active tDCS condition will show larger proximal (i.e., SOP) gains than the
SOP CRT + sham tDCS condition. Hypothesis 2: The active tDCS condition will demonstrate
generalization to secondary neurocognitive domains compared to the sham tDCS condition.
that tDCS will augment SOP cognitive remediation therapy (CRT) in older HIV+ adults. The
investigators will randomly assign 60 HIV+ older adults (i.e., ≥ 50 years old) to 10-hours
in either a SOP CRT + sham tDCS condition (n=30) or SOP CRT + active tDCS condition (n=30)
and examine neurocognitive functioning at baseline and 6 weeks post-intervention. Hypothesis
1: The SOP CRT + active tDCS condition will show larger proximal (i.e., SOP) gains than the
SOP CRT + sham tDCS condition. Hypothesis 2: The active tDCS condition will demonstrate
generalization to secondary neurocognitive domains compared to the sham tDCS condition.
Inclusion Criteria:
- HIV+
- Aged 50 and older
- Patient at University HIV/AIDS Clinic
Exclusion Criteria:
- Not homeless
- Not blind or deaf
- No significant neuromedical issues (e.g., schizophrenia, bipolar disorder, stroke,
epilepsy or history of seizures)
- No pacemaker or other biomedical devices or metal implants
- No untreated hypertension
- Not undergoing chemo or radiation
- No head injury with LOC greater than 30 mins
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