Telephone-Based Intervention in Increasing Adherence to Adjuvant Hormonal Therapy in Patients With Breast Cancer

PRIMARY OBJECTIVES:

I. Pilot test intervention effects on adherence to adjuvant hormonal therapy (AHT) and
explore trends in the adherence outcomes by demographic and psychosocial factors defined as
acceptance, continuation, and adherence.

SECONDARY OBJECTIVES:

I. Feasibility of study design defined as recruitment rate, rate of using intervention as
instructed, rate of protocol completion, and completion of psycho-social questionnaires which
have been associated with adherence to AHT in the existing literature (i.e., depression,
social support, pain, stress, fatigue, quality of life, pill taking attitude and behavior,
perceived risk of breast cancer recurrence).

TERTIARY OBJECTIVES:

I. Surveying patients and physicians regarding their comments on the intervention components
(i.e., video, text messaging, and app [application]) and overall study participation.

OUTLINE:

Patients receive daily text messages reminding them to take AHT and weekly interactive
surveys delivered by a smart phone app for 3 months.

Inclusion Criteria:

- Eligible women are those who:

- Are post-menopausal, verified by:

- Post bilateral surgical oophorectomy; or

- No spontaneous menses >= 1 year; or

- No menses for < 1 year with follicle stimulating hormone (FSH) and estradiol
levels in postmenopausal range, according to institutional standards

- Are diagnosed with primary breast cancer (BC) (stages I-III)

- Eligible to receive AHT (tamoxifen or an aromatase inhibitors [AI]) for the first time

- Completed all primary treatment

- Own a smartphone (in order to receive text messages and utilize the phone app)

- Agree to receive text messages on their smartphone over a 3-month period

- Provide consent and permission to review their medical records

- Plan to stay in the study area for 3 months