Effect of Caffeine on Heart Function



Status:Completed
Conditions:Other Indications, Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases, Other
Healthy:No
Age Range:18 - 35
Updated:4/2/2016
Start Date:March 2014
End Date:December 2015
Contact:Robert M Brothers, Ph.D.
Email:r.m.brothers@austin.utexas.edu
Phone:512-232-6016

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An Evaluation of the Heart Rate, Blood Pressure and Repolarization Effects of an Energy Drink as Compared to Coffee

- The primary objective of this study is to assess the effect of an energy drink on
ventricular repolarization as measured by the interval between the cardiac Q wave and
the cardiac T wave (QT interval)obtained from the body surface ECG.

- The secondary objective is to assess the effects of an energy drink on heart rate and
blood pressure (hemodynamic effects).

To place the observed changes in context, comparison will be made to a commonly consumed
drink, coffee: Starbuck's K-cup Breakfast Blend.

This study will assess cardiac repolarization before and after three conditions each of
which will involve the subject drinking beverages of varying caffeine content.

Inclusion Criteria:

- Healthy

- BMI between 24 - 29

Exclusion Criteria:

- Resting heart rate below 60 bpm

- Resting heart rate above 88 bpm

- Cardiovascular or metabolic disease
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