Cough in Reduced True Vocal Fold Mobility

The study investigators will consecutively recruit 30 adults diagnosed with vocal fold
insufficiency due to reduced mobility of one true vocal fold.

A questionnaire will be used to collect participants' information. Demographic information
such as age, gender, race/ethnicity, height, weight, and a major complaint (dysphonia and/or
dysphagia) and medical history information determining the eligibility for participation
will be collected from the participant. Participant's medical and surgical history
specifically related to the diagnosis and the etiology of reduced vocal fold mobility will
be obtained from the participant's medical record.

Videolaryngoscopy will be performed as part of standard clinical care. Vocal fold image and
cough airflow will be recorded simultaneously during voluntary cough production with the
flexible endoscope in nasopharynx. A second part of the study will include spirometry and
expiratory muscle strength assessments. Video images of the vocal fold movement during vowel
phonation and cough production will be recorded and stored on a CD for later analysis. The
cough airflow recordings will be displayed, stored, and analyzed using LabChart software for
Windows.

Inclusion Criteria:

1. Age between 40 and 75 years.

2. Glottal insufficiency secondary to reduced TVF mobility confirmed with the endoscopic
evaluation performed by an otolaryngologist.

3. The ability to provide informed consent.

4. No history of chronic obstructive pulmonary disease, lung cancer, and/or lung
transplant.

5. No history of neurodegenerative disease such as Parkinson's disease, multiple
sclerosis (MS), amyotrophic lateral sclerosis (ALS), or progressive supranuclear
palsy (PSP), Alzheimer's disease, or dementia.

Exclusion Criteria:

1. Chest infection within one month prior to the study participation.

2. History of the adverse reaction associated with laryngoscopy.