The Randomized Controlled Cocoa-Appetite Trial



Status:Completed
Conditions:Obesity Weight Loss
Therapuetic Areas:Endocrinology
Healthy:No
Age Range:18 - 35
Updated:4/21/2016
Start Date:March 2015
End Date:May 2015

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A Pilot Randomized Human Trial on The Effects of Cocoa on Appetite.

The purpose of this study is to determine whether high-flavonoid cocoa can decrease appetite
in humans. In addition the study is designed to test epicatechin, a compound found in cocoa
and procyanidins, a class of compounds found in cocoa, for their ability to decrease
appetite in humans.

The study is a four-way randomized double-blinded crossover trial with randomization
balanced for beverage and lab visit order.

Inclusion Criteria:

- stable-weight, as indicated by weight gain or loss of <2% in the past 6 months;

- engaging in only mild exercise< twice a week;

- moderate alcohol users, <2 drinks/day;

- willing to eat pizza.

- mentally and physically healthy.

Exclusion Criteria:

- smokers regular;

- frequent drinkers of coffee, tea or cola sodas, >daily;

- underweight or obese (BMI: <18.5 or >30 Kg/m2);

- allergies to chocolate, cocoa, green tea, coffee or pizza;

- using medication;

- interested in registering in the future for the course Health & Nutrition Sciences
2140, Introduction to the U.S. Health Care System, that is often taught by the PI of
the proposed study
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