Clear Care® Plus vs. PeroxiClear™



Status:Completed
Conditions:Ocular
Therapuetic Areas:Ophthalmology
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:April 2015
End Date:August 2015

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Comparison of Two One-Step Hydrogen Peroxide Lens Care Solutions in Symptomatic Contact Lens Wearers

The purpose of this study is to evaluate Clear Care® Plus compared to PeroxiClear™ for mean
residual peroxide in used lens cases collected at Day 30.

The subject will wear habitual lenses on a daily wear basis and use the assigned test
solution for daily lens care.

Inclusion Criteria:

- Sign informed consent form;

- Adapted, 2-week/monthly replacement silicone hydrogel contact lens wearers (at least
2 months);

- Willing to wear study lenses daily wear only on a daily basis (7 days per week and at
least 4 hours per day) and attend all study visits;

- Symptoms of contact lens related dryness as defined by the Symptomatic Pre-Screening
Questionnaire;

- Other protocol-specified inclusion criteria may apply.

Exclusion Criteria:

- Current hydrogen peroxide-based solution user;

- Routinely sleeps in lenses at least 1 night per week over the last 3 months prior to
enrollment;

- Ocular anterior segment infection, inflammation, abnormality, or active disease that
would contraindicate contact lens wear;

- Any systemic diseases that may affect the eye or be exacerbated by use of contact
lenses or contact lens solutions or which could prevent wearing lenses at least 4
hours per day;

- Use of systemic or ocular medications for which contact lens wear could be
contraindicated;

- Monocular (only 1 eye with functional vision) or fit with only 1 lens;

- History of herpetic keratitis, ocular surgery, or irregular cornea;

- Other protocol-specified exclusion criteria may apply.
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