Postoperative Respiratory Monitoring After Neuraxial Opioid Administration for Cesarean Delivery
| Status: | Completed |
|---|---|
| Conditions: | Depression, Pulmonary |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 45 |
| Updated: | 5/5/2017 |
| Start Date: | April 2015 |
| End Date: | April 15, 2016 |
Respiratory depression occurs in labor and delivery; noticeably when neuraxial opioids are
given.Pathophysiological respiratory depression -failure to respond to hypercapnia or
hypoxia - is challenging to measure clinically.American Society of Anesthesiologist
guidelines recommend suitable respiratory monitoring for 24 hours post cesarean delivery
(CD).
Use of capnograph will enable us to assess breath-by-breathe respiration in a population
receiving neuraxial opioids - potentially at risk for respiratory depression.
Our aim is to assess our ability to capture maternal postpartum respiratory parameters in a
cohort following opioid neuraxial administration for CD.
given.Pathophysiological respiratory depression -failure to respond to hypercapnia or
hypoxia - is challenging to measure clinically.American Society of Anesthesiologist
guidelines recommend suitable respiratory monitoring for 24 hours post cesarean delivery
(CD).
Use of capnograph will enable us to assess breath-by-breathe respiration in a population
receiving neuraxial opioids - potentially at risk for respiratory depression.
Our aim is to assess our ability to capture maternal postpartum respiratory parameters in a
cohort following opioid neuraxial administration for CD.
The investigators wish to test the efficacy of capnograph in detection of apnea and
respiratory depression in women following cesarean delivery. Currently, routine intensive
monitoring such as the investigators propose is not performed, and many apneas may go
undetected.
respiratory depression in women following cesarean delivery. Currently, routine intensive
monitoring such as the investigators propose is not performed, and many apneas may go
undetected.
Inclusion Criteria:
- American Society of Anesthesiologists physical status class I or II
- Age between 18 and 45
- Gestational age greater than 37 completed weeks
- Singleton pregnancy.
Exclusion Criteria:
- Contraindication for neuraxial analgesia (bleeding diathesis, neuropathy, severe
scoliosis, previous spine surgery, local anesthetic allergy)
- Allergies to postoperative medication (opioids, NSAIDs, acetaminophen)
- Chronic opioid use
- Opioid administration in the previous 12 hours
- Inability to adequately understand the consent form
- Blocked nose or nasal deformity.
We found this trial at
1
site
Palo Alto, California 94304
Principal Investigator: Brendan Carvalho, MD
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