Tai Chi for Enhancing Motor and Cognitive Function in Parkinson's Disease

Specific Aim 1: To assess the feasibility of recruiting and retaining individuals with PD
into a 6-month randomized controlled trial of Tai Chi exercise.

Specific Aim 2: To collect preliminary data on the efficacy of Tai Chi on improving gait and
balance dynamics, physical and cognitive function, exercise activity, self-efficacy, mood,
and quality of life in individuals with PD.

Inclusion Criteria:

- Individuals recently diagnosed with idiopathic PD (≤ 10 years)

- Limited disease progression

- If taking PD-related medication, willingness to undergo baseline and follow-up
testing while off medication

- Willingness to commit to the study protocols and complete Tai Chi program

- Willingness to be videotaped and audio-recorded during testing

Exclusion Criteria:

- Diagnosis of any form of atypical parkinsonism

- History of: stroke, head trauma, brain tumor, brain injury, seizures or other central
nervous system condition, orthopedic impairment or other disease that could likely
contribute to a gait disturbance or parkinsonism

- Any severe, chronic condition or acute medical event for which participation in
exercise programs is contraindicated (e.g. debilitating Rheumatoid Arthritis, history
of frequent falls, unhealed fracture)**

** Unless the participant is able to obtain formal written approval from his/her
treating physician granting permission to participate in our Tai Chi exercise program

- Participation in brain stimulation within the past 3 months

- Family history of seizures or unexplained loss of consciousness

- Current history of dementia or severe psychiatric illness. Patients with mild
(non-suicidal) depression and/or anxiety may be included

- Acute illness requiring hospitalization within past 3 months

- History of deep brain stimulation or other brain surgery

- Participation in brain stimulation within the past 3 months

- Regular use of walking aid

- Significant Tai Chi experience (> 6 months training in past 2 years)