Liposomal Bupivacaine in Total Knee Arthroplasty
| Status: | Withdrawn |
|---|---|
| Conditions: | Arthritis, Osteoarthritis (OA), Post-Surgical Pain, Orthopedic |
| Therapuetic Areas: | Musculoskeletal, Rheumatology, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 4/21/2016 |
| Start Date: | June 2015 |
| End Date: | June 2017 |
Analgesic Efficacy of Liposomal Bupivacaine in Total Knee Arthroplasty
Liposomal bupivacaine is a novel local anesthetic designed for prolonged pain relief.
Despite its long-acting analgesic potential, liposomal bupivacaine is significantly more
expensive than other local anesthetic alternatives. The primary aim of this investigation is
to examine whether or not liposomal bupivacaine provides superior pain relief or clinically
significant opioid-sparing effects versus a control to justify its cost.
Despite its long-acting analgesic potential, liposomal bupivacaine is significantly more
expensive than other local anesthetic alternatives. The primary aim of this investigation is
to examine whether or not liposomal bupivacaine provides superior pain relief or clinically
significant opioid-sparing effects versus a control to justify its cost.
Inclusion Criteria:
- Patients undergoing a primary unilateral total knee arthroplasty by the PI of the
trial
Exclusion Criteria:
- Patients with a sensitivity to marcaine
- Pregnant or lactating women
- Non-English speaking individuals
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