The Effect of Prefrontal Cortex Stimulation on Antisocial and Aggressive Behavior



Status:Active, not recruiting
Conditions:Psychiatric
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - Any
Updated:4/17/2018
Start Date:March 2015
End Date:December 2018

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The Effect of Transcranial Direct Current Stimulation of the Prefrontal Cortex on Antisocial and Aggressive Behavior

This study investigates the effect of upregulating prefrontal cortex activity on antisocial
and aggressive behavior and risk factors for such behavior. In the double-blind, randomized
controlled trial, participants will undergo anodal transcranial direct current stimulation
bilaterally to the dorsolateral prefrontal cortex or a sham stimulation. During and after
stimulation, they will complete survey and laboratory measures assessing antisocial and
aggressive behavior and risk factors for antisocial and aggressive behavior. Heart rate and
skin conductance will also be measured.


Inclusion Criteria:

- Above 18 years of age

- Able to understand the nature of the study and give informed consent

Exclusion Criteria:

- History of or active neurologic, cardiovascular, or psychiatric disease

- Currently consuming anti-convulsant, anti-psychotic, or sedative/hypnotic medications

- Currently consuming anti-depressants

- History of seizures

- Metallic implants on the scalp

- Participation in other transcranial magnetic stimulation (TMS) or tDCS experiments on
the same day

- History of adverse reactions to tDCS
We found this trial at
1
site
3451 Walnut St
Philadelphia, Pennsylvania 19104
1 (215) 898-5000
Phone: 215-746-4390
Univ of Pennsylvania Penn has a long and proud tradition of intellectual rigor and pursuit...
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