Acoustic Stimulation Paired With Body and Cortical Stimulation for Modulating Tinnitus
| Status: | Completed |
|---|---|
| Conditions: | Other Indications |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 9/15/2017 |
| Start Date: | June 2015 |
| End Date: | September 13, 2017 |
The purpose of the study is to investigate different stimulation parameters for a new
noninvasive approach for modulating the brain that could potentially be beneficial for
decreasing tinnitus perception. The new approach is called Multimodal Synchronization Therapy
(mSync). mSync uses a combination of acoustic stimulation played through headphones and low
levels of electrical current delivered via electrodes placed on the surface of different body
regions. The timing interval between the acoustic and body stimulation is varied in order to
cause different types of changes in the brain. In addition to acoustic and body stimulation,
noninvasive cortical stimulation will also be presented as part of mSync to attempt to
further modulate or decrease the tinnitus percept. Cortical stimulation will be performed by
placing a magnetic coil over a spot on the head and sending a brief magnetic pulse that can
travel through the skin and bone to create electrical current inside the head. For this
study, different body locations as well as specific timing intervals among acoustic, body,
and cortical stimulation will be investigated to identify appropriate parameters that can
modulate and potentially decrease tinnitus perception. Different mSync parameters will be
investigated across multiple testing sessions (up to 16 weekly sessions) and the tinnitus
percept will be closely monitored throughout the study.
noninvasive approach for modulating the brain that could potentially be beneficial for
decreasing tinnitus perception. The new approach is called Multimodal Synchronization Therapy
(mSync). mSync uses a combination of acoustic stimulation played through headphones and low
levels of electrical current delivered via electrodes placed on the surface of different body
regions. The timing interval between the acoustic and body stimulation is varied in order to
cause different types of changes in the brain. In addition to acoustic and body stimulation,
noninvasive cortical stimulation will also be presented as part of mSync to attempt to
further modulate or decrease the tinnitus percept. Cortical stimulation will be performed by
placing a magnetic coil over a spot on the head and sending a brief magnetic pulse that can
travel through the skin and bone to create electrical current inside the head. For this
study, different body locations as well as specific timing intervals among acoustic, body,
and cortical stimulation will be investigated to identify appropriate parameters that can
modulate and potentially decrease tinnitus perception. Different mSync parameters will be
investigated across multiple testing sessions (up to 16 weekly sessions) and the tinnitus
percept will be closely monitored throughout the study.
This study is not specifically seeking to treat tinnitus but is designed to investigate
various mSync parameters that can alter the tinnitus percept. Findings from this study will
help identify specific mSync parameters that can be more effective at decreasing or fully
suppressing the tinnitus percept that will be systematically explored in a follow-up study.
various mSync parameters that can alter the tinnitus percept. Findings from this study will
help identify specific mSync parameters that can be more effective at decreasing or fully
suppressing the tinnitus percept that will be systematically explored in a follow-up study.
Inclusion Criteria:
- Have subjective, non-pulsatile, and bothersome tinnitus
- Will not start any new tinnitus treatment during the study
- Ability to give informed consent and understand study objectives in English
- Willing and able to understand and comply with all study-related procedures
Exclusion Criteria:
- Substantial hearing loss or hyperacusis that may interfere with the study
- Medical history of other ear or brain disorders, history of seizures, or currently
using any medication or treatments that can cause or increase the chances of seizures
- Any implanted medical or metal device, such as a pacemaker, aneurysm clip, or cochlear
implant
- Pregnant or currently breast-feeding (we need to give all female subjects a pregnancy
test because pregnant females and unborn children need extra protection for their
safety)
- Any handicap that prevents the subject from reliably performing the tests
We found this trial at
1
site
Minneapolis, Minnesota 55455
Principal Investigator: Hubert Lim, PhD
Phone: 612-626-4010
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