Evaluating a Novel Onco-genetic BRCA Testing Counselling Model Among Patients With Ovarian Cancer

This will be a prospective observational study of patients diagnosed with epithelial
ovarian/fallopian tube/primary peritoneal cancer prior to, or at enrolment in this study. The
study is descriptive in nature and does not attempt to test any specific a priori hypotheses.

Clinical teams (physicians and nurses) will be trained to discuss BRCA testing with ovarian
cancer patients who meet study criteria and consent to participate in the study. Patients
will be recruited from participating sites in North America and Europe. Patients selected per
the study inclusion and exclusion criteria will be consented for participation in the study.
Patients will be recruited during an estimated 12 month period and participating patients
will be followed from enrollment in the study until provision of BRCA test results, final
genetics counselling, and completion of satisfaction survey or death. A case report form will
be developed to collect information on the primary variable of interest (i.e., turnaround
time), patient and disease characteristics, medical history, treatment patterns and outcome
of the BRCA test. In addition, a survey will be developed to evaluate patient's assessment of
pre- BRCA onco-genetic counseling quality and satisfaction with onco-genetic testing process.

Finally, surveys will be developed to evaluate oncologist (or oncology nurse) and genetic
counselor's assessment of the processes associated with the onco-genetic testing pathway.

Inclusion Criteria:

- Patients diagnosed with epithelial ovarian/fallopian tube/primary peritoneal cancer

- Patients aged 18 years or older at ovarian cancer diagnosis

- Provision of written informed consent

- Patient is able to read, write, and understand the material presented to them as part
of this study, per the discretion of the physician

Exclusion Criteria:

- Patients with low grade epithelial ovarian cancer or non-epithelial ovarian cancer

- Patients enrolled in an interventional clinical trial for ovarian cancer or other
malignancy at the time of conduct of this study

- Patients with BRCA testing any time prior to the study enrollment