Elastography as Gouty Arthropathy Outcome (EGO)

Pilot study to assess 10 subjects with tophaceous gout on urate lowering therapy or about to
begin urate lowering therapy.

Inclusion Criteria:

1. Subjects who are at least 18 years of age but younger than or equal to 99 years of
age.

2. Subjects with gouty arthritis as determined by the ACR 1977 classification criteria
for gouty arthritis.

3. Subjects with one palpable tophus detectable by one of the three clinical parameters
described.

Exclusion Criteria:

1. Subjects who are not eligible for urate lowering treatment or show a hypersensitivity
to these drugs or class of compounds.

2. Subjects with significant cardiovascular, neuropsychiatric, hematologic, hepatic,
renal or endocrine dysfunction who in the opinion of the principal investigator are
unfit for participation in a clinical trial.

3. Subjects for which the clinical and laboratory assessment would provide undue
discomfort and / or are contraindicated.