Exercise and Body Composition in Juvenile Idiopathic Arthritis



Status:Completed
Conditions:Arthritis
Therapuetic Areas:Rheumatology
Healthy:No
Age Range:10 - 21
Updated:4/17/2018
Start Date:July 2012
End Date:October 2015

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"Joint Fitness": A Double-Armed Controlled Intervention to Assess the Safety and Effectiveness of Resistance Exercise Training on Muscle, Bone, Strength, Symptoms, Quality of Life and Biological Parameters in Children and Young Adults With JIA

This research is being done to see if resistance exercise (RE) is safe and has a positive
effect on children and young adults with juvenile idiopathic arthritis (JIA).

JIA is an inflammatory autoimmune disease that can cause severe impairment and disability.
JIA can cause bone loss and decreased muscle strength. The medications used to treat JIA can
also have negative effects on growth and development, strength, and ability to function. RE
is performing movements in a slow and controlled fashion (i.e., no speeding up or using force
in the lifting and lowering of the weight) to lessen force on the joints and tissues. This
study will be using Ren-Ex exercise equipment to perform RE.

Currently the American College of Rheumatology recommends exercise for patients with
arthritis. This exercise includes range of motion exercise to protect joint mobility as well
as low resistance and aerobic exercise (AE) to protect muscle mass, bone health, and fitness.
However, a recent study showed no major differences in functionality or quality of life
between patients who performed AE and those who did not perform AE. There is a need for more
data on the impact of RE on children with JIA. Children and young adults aged 10 to 21 with
juvenile idiopathic arthritis may join.


Inclusion Criteria:

- American College of Rheumatology criteria for polyarticular JIA

- Stable medical therapy

Exclusion Criteria:

- Non-English speaking

- Pregnancy

- Currently breast feeding

- Cognitive impairment as determined by PI (patient is not responsible for making their
own health care decisions)
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Baltimore, Maryland 21205
410-516-8000
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