Postoperative Nasal High Flow Versus Oxygen for Positive Airway Pressure Non-Compliance Sleep Apnea Patients

Patients identified preoperatively with previously diagnosed obstructive sleep apnea
(intermittent collapse of upper airway while asleep) who refuse Continuous Positive Airway
Pressure use after surgery and are treated with routine postoperative supplemental oxygen
alone (1 liters per minute) will have more oscillation of oxygen saturation during the night
(measure by overnight oximetry) than those treated with high nasal flow air insufflator
(Fisher & Paykel Airvo 2 device) with same amount of oxygen supplement (1 liters per minute).

Inclusion Criteria:

1. Known diagnosis of obstructive sleep apnea by polysomnography (Apnea Hypopnea Index ≥
5 events per hour) with recommendation of Continuous Positive Airway Pressure use.

2. The patient declines use of Continuous Positive Airway Pressure for the upcoming
elective surgery.

3. The patient will require more than 48 hours of hospitalization.

4. Informed consent obtained from patient or approved designate.

Exclusion Criteria:

1. Predetermined need for Continuous Positive Airway Pressure post-operatively by
surgical team.

2. Body Mass Index ≥ 40.

3. Patient with congestive heart failure and diagnosis of Cheyne- Stokes respiration or
central apnea.

4. Patients who are oxygen dependent due to moderate to severe Chronic Obstructive
Pulmonary Disease (Available Forced Expiratory Volume at 1 second of < 50% predicted)
or advanced interstitial lung disease.

5. Preexisting chronic hypercapnia with known neuromuscular disease with respiratory
involvement (e.g. Amyotrophic Lateral Sclerosis, myopathy).

6. Severe anemia necessitating blood transfusion.

7. Presence of tracheostomy.

8. Naso-oral malformation or severe nasal septal defect.

9. Presence of dementia or other diagnosed neurodegenerative disease.

10. Non-English speakers

11. Inability to provide informed consent.