Comparison of Smoking and Vaping in Families

The current study seeks to compare health-related outcomes among youth who reside with
non-smokers, cigarette smokers, and electronic cigarette users.

Control Group: will consist of participants ages 6 - 17 who live in a home with adults who do
not smoke. A brief breathing test will verify a non-smoker and/or are not around a certain
amount of smoke in the environment (live with a smoker). The participant will be asked to
complete a series of brief questionnaires that asks about basic demographic information,
medical history, and that asks about their smoking history. The participant's will also be
asked to complete two 5 minute breathing tests, provide a sample of saliva, a urine sample,
and have their toe nails clipped.

Vaping Group: will consist of participants ages 6 -17 who live in a home with adults who
currently use electronic cigarettes. A brief breathing test will verify a non-tobacco smoker
and/or are not around a certain amount of smoke in the environment (live with a tobacco
smoker). The participant will be asked to complete a series of brief questionnaires that asks
about basic demographic information, smoking or vaping history and patterns of use, and
medical history. The participant will be asked to complete two 5 minute breathing tests,
provide a sample of saliva, a urine sample, and have their toe nails clipped.

Smoking Group: will consist of participants ages 6 - 17 who live in a home with adults who
currently smoke cigarettes. Participants will then be asked to complete a series of brief
questionnaires that asks about basic demographic information, smoking or vaping history and
patterns of use, and medical history. The participant will also be asked to complete two 5
minute breathing tests, provide a sample of saliva, a urine sample, and have their toe nails
clipped.

Inclusion Criteria:

For the control group the caregiver must self-report:

1. never smoking or not smoking for at least the past 12 months;

2. that no one living in the home is a current smoker or has smoked in the home for the
past 6 months; and

3. have a breath carbon monoxide reading of ≤ 6ppm.

For the smoking group caregivers must:

1. smoke at least 10 cigarettes per day for the past year;

2. indicate that they smoke in the car or home ≥ 3 times per week; and

3. do not use non-cigarette tobacco (e.g., cigars, chewing tobacco).

For the vaping group caregivers must:

1. exclusively use EC for the past 3 months (no cigarette or other tobacco use); and

2. no one living in the home is a current tobacco smoker or has smoked in the home for
the past 6 months; and

3. have a breath carbon monoxide reading of ≤ 6ppm.