Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology

Status:	Recruiting
Conditions:	Cancer, Cancer, Cancer
Therapuetic Areas:	Oncology
Healthy:	No
Age Range:	18 - Any
Updated:	8/26/2018
Start Date:	July 21, 2015
End Date:	July 2019
Contact:	Snehal Patel, MD
Phone:	212-639-3412

The purpose of this study is to get images (pictures) of oral lesions, which occur inside the
mouth, before the patient's surgery using a special camera. These pictures will be used in
our research to evaluate a new technology that uses a laser and takes pictures of the
microscopic structure of tissue. The technology is called "reflectance confocal microscopy."
We would like to compare what the camera sees to biopsies (pathology) of the same area. We
will evaluate the pictures obtained from the patient to determine whether this technology may
be useful in the future. We hope this technology can be used as a tool for early diagnosis of
oral cancers and for guiding surgery.

Inclusion Criteria:

- Patients with biopsy-proven oral SCC who are scheduled to undergo surgery in the MSK
Head and Neck Service.

- Ability to sign informed consent.

- Age ≥ 18 years.

Exclusion Criteria:

- Cancer located on a site that may not be convenient or accessible for imaging with the
current version of the RCM device (gingivobuccal region, back of the oral cavity, back
of the tongue, floor of the mouth, deep under the tongue, etc.).

- Inability to give informed consent.

We found this trial at

sites

Memoral Sloan Kettering Monmouth

480 Red Hill Road
Middletown, New Jersey 07748

Phone: 212-639-3412

from

Middletown, NJ