Endotracheal Intubation Among the Critically Ill: HEMAIR Pilot Study

Aim 1: To derive and validate a prediction model for difficult airway (three or more attempts
at laryngoscopy to place an endotracheal tube and/or the need for another operator among the
critically ill) [37].

Aim 2: To derive and validate a prediction model for hemodynamic compromise, i.e.,
post-intubation hypotension [defined as a decrease at any point in mean arterial pressure
less than 65 mmHg; systolic blood pressure less than 80 mm Hg and/or a reduction in systolic
blood pressure of 40% from baseline; or the initiation of, or increase in infusion dosage of,
any vasopressor medication (bolus or infusion) during the 30 minute period following
intubation] [38-39].

Aim3: To derive and validate a predication model for hypoxemia (decrease in pulse oximetry to
oxygen saturation less than 88% during the procedure).

Inclusion Criteria:

- Patient age ≥ 18 years

- Surgical and medical intensive care unit adult patients

- Adult patients requiring endotracheal intubation during the time period of study

Exclusion Criteria:

- Patient age < 18 years

- Endotracheal intubations performed outside the ICU (in the operating room, in and
outside the hospital) are excluded