Optical Coherence Tomography of Airway and Pleural Disorders



Status:Recruiting
Healthy:No
Age Range:18 - Any
Updated:4/21/2016
Start Date:July 2007
End Date:July 2018
Contact:Matthew Brenner, M.D
Email:mbrenner@uci.edu
Phone:(714) 456-5150

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The researcher can use Optical coherence tomography a near-infrared diode to emit light that
can produce images of the specimen under investigation and provide information about tissue
abnormalities without causing damage.

The researcher can use Optical coherence tomography endoscopic imaging to improve diagnosis
and treatment of airway and pleural malignancy. In the events of burn injury and smoke
inhalation injury, the Optical coherence tomography can determine the change of the airway
tissues and severity of airway injury.

During endoscopic procedure the lesions will be biopsied and prepared by standard histologic
methods. The Optical coherence tomography endoscopic imaging can measured histologic of the
tissue samples and compared to standard histologic examination. The Optical coherence
tomography endoscopic imaging can measured the epithelial thickness and compared to visual
inspection of the mucosa on bronchoscopy.

Inclusion Criteria:

- Adult 18 or older, male or female.

- Plans for bronchoscopic with possible biopsy procedures.

Exclusion Criteria:

- Age less than 18 years of age

- Not plan for bronchoscopic with possible biopsy procedures.

- Pregnant or breastfeeding.
We found this trial at
1
site
Irvine, California 92612
Principal Investigator: Matthew Brenner, M.D
Phone: 714-456-5150
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Irvine, CA
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