A Pilot Study to Evaluate Multi-Spectral Imaging and Laser Speckle Imaging During Vascular Occlusion
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | November 2011 |
| End Date: | November 2018 |
| Contact: | Ata Sharif, MD |
| Email: | sharifs@uci.edu |
| Phone: | 949-824-9265 |
The purpose of this research is to evaluate and validate the performance of non-invasive
imaging modalities for assessment of skin. A pressure cuff occlusion will be used to
stimulate blood flow dynamic that these instruments are designed to sense. The researcher
currently plan to assess only basic feasibility of the imaging instruments.
imaging modalities for assessment of skin. A pressure cuff occlusion will be used to
stimulate blood flow dynamic that these instruments are designed to sense. The researcher
currently plan to assess only basic feasibility of the imaging instruments.
The primary reason for including pressure cuff occlusion in this protocol is to test the
performance of Multi-Spectral Imaging and Laser Speckle Imaging can measure in the full
range of vascular conditions ranging from ischemic (under-perfused or unsaturated) to
hyperemic (over-perfused and over-saturated).
1. .Modulated Imaging a non-contact optical imaging technology can detect the
concentration of total hemoglobin, deoxygenated and oxygenated hemoglobin in absolute
amounts in units of millimoles / unit volume of tissue measured.
2. . Laser Speckle Imaging a non-contact optical imaging technology consists of a coherent
light source, camera, and image acquisition system. This image device can measure and
compare relative flow in vasculature at varied time points.
performance of Multi-Spectral Imaging and Laser Speckle Imaging can measure in the full
range of vascular conditions ranging from ischemic (under-perfused or unsaturated) to
hyperemic (over-perfused and over-saturated).
1. .Modulated Imaging a non-contact optical imaging technology can detect the
concentration of total hemoglobin, deoxygenated and oxygenated hemoglobin in absolute
amounts in units of millimoles / unit volume of tissue measured.
2. . Laser Speckle Imaging a non-contact optical imaging technology consists of a coherent
light source, camera, and image acquisition system. This image device can measure and
compare relative flow in vasculature at varied time points.
Inclusion Criteria:
- Male and female adult 18 years and older
Exclusion Criteria:
- Younger than 18 years of age
- Pregnant women
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