Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections
| Status: | Completed |
|---|---|
| Conditions: | Infectious Disease, Hospital |
| Therapuetic Areas: | Immunology / Infectious Diseases, Other |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 8/18/2018 |
| Start Date: | August 2015 |
| End Date: | June 21, 2018 |
A Randomized Controlled Trial of 2% Chlorhexidine Gluconate Skin Preparation Cloths for the Prevention of Post-Operative Surgical Site Infections in Colorectal Patients
Use of 2% chlorhexidine gluconate cloths pre-operatively and daily post-operatively jaw line
to toes will decrease surgical site infections (SSI) by 30% when compared to patients who
receive routine standard of care (use of chlorhexidine cloths night before surgery and
morning of surgery).
to toes will decrease surgical site infections (SSI) by 30% when compared to patients who
receive routine standard of care (use of chlorhexidine cloths night before surgery and
morning of surgery).
Patients undergoing colorectal surgery will be randomized in a 1:1 fashion into two groups.
One will be standard of care using 2% Chlorhexidine Gluconate wipes night before surgery and
morning if surgery. The second group will be randomized into the study arm using 2%
Chlorhexidine Gluconate clothes from jaw line to toes night before surgery, morning of
surgery and daily post operative. Skin cultures will be obtained at time of consent, prior to
surgical procedure before surgical scrub and draping, post operative day 4 and at 30 day
follow up visit. Incision lines will be assessed daily by study staff for signs of surgical
site infection utilizing the CDC's 3 definitions of surgical site infections, superficial
incisional SSI, deep incisional SSI, and organ space SSI.
One will be standard of care using 2% Chlorhexidine Gluconate wipes night before surgery and
morning if surgery. The second group will be randomized into the study arm using 2%
Chlorhexidine Gluconate clothes from jaw line to toes night before surgery, morning of
surgery and daily post operative. Skin cultures will be obtained at time of consent, prior to
surgical procedure before surgical scrub and draping, post operative day 4 and at 30 day
follow up visit. Incision lines will be assessed daily by study staff for signs of surgical
site infection utilizing the CDC's 3 definitions of surgical site infections, superficial
incisional SSI, deep incisional SSI, and organ space SSI.
Inclusion Criteria:
- 1. Patients > 18 years old scheduled for a colorectal surgical procedure ASA>2 OR
pre-operatively hospitalized
Exclusion Criteria:
- Unable to consent
- Known allergy to any of the ingredients contained in SAGE chlorhexidine gluconate
cloths
- Current infection or history of abdominal infections.
- Patients on chronic steroids or immunosuppressive medications.
We found this trial at
1
site
2201 West End Ave
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-7311
Principal Investigator: Steven Klintworth, RN
Vanderbilt University Vanderbilt offers undergraduate programs in the liberal arts and sciences, engineering, music, education...
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