Granulation Tissue Treatment: Silver Nitrate vs Kenalog vs Washcloth Abrasion
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | Any - 17 |
| Updated: | 10/24/2018 |
| Start Date: | January 15, 2015 |
| End Date: | July 2019 |
| Contact: | Tina Thomas, MBBS |
| Email: | tinath@med.umich.edu |
| Phone: | 734-320-7568 |
Granulation Tissue at G Tube Site: Treatment With Kenalog vs Chemical Cauterization With Silver Nitrate vs Soap Washcloth Abrasion
Granulation tissue, or excess tissue, forms around gastrostomy tube sites and is a common
problem seen in the pediatric surgery population. There is no standard treatment that has
been identified in clinical practice to treat granulation tissue effectively. Clinicians
prescribe treatments of varying nature to help treat this condition. By conducting this
study, the investigators hope to identify if there is any difference in the treatment groups
and if there is any superiority for one treatment over the other. The three arms in the study
are Silver Nitrate treatment, treatment with Kenalog, and Washcloth abrasion. Treatments will
continue over a period of three weeks, and the progress will be followed using surveys and
photographs.
problem seen in the pediatric surgery population. There is no standard treatment that has
been identified in clinical practice to treat granulation tissue effectively. Clinicians
prescribe treatments of varying nature to help treat this condition. By conducting this
study, the investigators hope to identify if there is any difference in the treatment groups
and if there is any superiority for one treatment over the other. The three arms in the study
are Silver Nitrate treatment, treatment with Kenalog, and Washcloth abrasion. Treatments will
continue over a period of three weeks, and the progress will be followed using surveys and
photographs.
Hypergranulation tissue surrounding gastrostomy tube sites in pediatric patients is a
significant problem. This tissue may cause drainage or bleeding that bothers patients and
parents. Numerous methods of treatment are used for treatment of hypergranulation tissue, but
no data exists to support one method of treatment over another. The investigators plan to
perform a prospective randomized trial of three different therapies (silver nitrate
cauterization, topical kenalog, and soapcloth abrasion) to identify the best treatment
modality. Participants will be followed via office visit at four and eight weeks after
initiation of therapy. Measurements of the granulation tissue and photographs will be
obtained pre treatment and at each post treatment visit. In addition parents will be asked to
fill out a pre and post treatment survey regarding improvement in symptoms. Investigators
plan to enroll 120 patients total with the intention of having 40 participants in each group.
significant problem. This tissue may cause drainage or bleeding that bothers patients and
parents. Numerous methods of treatment are used for treatment of hypergranulation tissue, but
no data exists to support one method of treatment over another. The investigators plan to
perform a prospective randomized trial of three different therapies (silver nitrate
cauterization, topical kenalog, and soapcloth abrasion) to identify the best treatment
modality. Participants will be followed via office visit at four and eight weeks after
initiation of therapy. Measurements of the granulation tissue and photographs will be
obtained pre treatment and at each post treatment visit. In addition parents will be asked to
fill out a pre and post treatment survey regarding improvement in symptoms. Investigators
plan to enroll 120 patients total with the intention of having 40 participants in each group.
Inclusion Criteria:
- Any patient falling within age group with granulation tissue around G tube site
Exclusion Criteria:
- Patients falling outside of age group range
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