Outpatient Treatment of PE and DVT in the Emergency Department

In the current protocol, we will study the outcomes most likely to influence emergency
physician behavior, such as improved Emergency Department (ED) throughput, and decreased ED
and Emergency Department Observation Unit (EDOU) length of stay. Metrics such as decreased
admissions are also very important to hospital administrators so our results will have impact
outside the ED as well. At the end of this study we will demonstrate that a carefully planned
and data-driven approach to the outpatient treatment of Pulmonary Embolism (PE) is safe,
improves operational metrics, and reduces cost.

Inclusion Criteria:

- Subject is 18 years of age or older at time of enrollment.

- Subject is diagnosed with acute VTE (DVT or PE) in the MGH or BWH ED or transferred to
the MGH or BWH ED (e.g from a clinic or outside hospital) with a diagnosis of acute
VTE.

- Subject is treated as an outpatient (i.e. discharged) directly from the ED or admitted
to the ED Observation Unit/ED Short Stay Unit on the outpatient treatment protocol.

Exclusion Criteria:

- Subjects admitted from the ED to an inpatient service will not be enrolled as study
subjects, but will be used as contemporary controls.

- Subjects who are unable to understand or provide informed consent.

- Subjects unable or unlikely to follow up (e.g. prisoners).