Comparative Volumetric Assessment of Alveolar Ridge Preservation Utilizing Different Bone Grafting Materials

Inclusion Criteria:

1. Provision of informed consent

2. ≥ 18 years and ≤ 75 years

3. Good physical health (ASAI/II)

4. Extraction of maxillary premolar, canine or incisor, or mandibular premolar and canine
required

5. Teeth adjacent (mesial and distal) to study site must consist of two stable natural
teeth with minimal restorations, without signs of periodontal bone loss (> 3 mm)
and/or significant soft tissue deficiencies

Exclusion Criteria:

1. Buccal plate dehiscence and/or fenestration >3mm at study site following extraction

2. Untreated rampant caries and uncontrolled periodontal disease

3. Inadequate oral hygiene (estimated plaque score >20%)

4. Smokers using more than 10 cigarettes or equivalent per day

5. Smokeless tobacco use or e-cigarette use

6. Compromised physical health and/or uncontrolled or severe systemic diseases including:

ASA III/IV Metabolic bone disease History of malignancy History or radiotherapy or
chemotherapy for malignancy in the past 5 years History of autoimmune disease
Long-term steroidal or antibiotic therapy Uncontrolled diabetes Known alcohol or drug
abuse

7. Systemic or local disease or condition that would compromise post-operative healing

8. Use of any substance or medication that will influence bone metabolism

9. Known pregnancy

10. Unable or unwilling to return for follow-up visits for a period of 6 months

11. Unlikely to be able to comply with study procedures according to Investigators
judgement

12. Involvement in the planning and conduct of the study

13. Previous enrollment or randomization of treatment in the present study