Dopamine Receptor Agonist Therapy for Pain Relief in Women Suffering From Endometriosis: A Pilot Study
| Status: | Completed |
|---|---|
| Conditions: | Women's Studies, Endometriosis |
| Therapuetic Areas: | Other, Reproductive |
| Healthy: | No |
| Age Range: | 15 - 40 |
| Updated: | 10/26/2018 |
| Start Date: | May 2016 |
| End Date: | September 2018 |
The proposed pilot study will estimate the efficacy and safety of a novel therapeutic agent,
cabergoline, with a clinical standard therapy, norethindrone acetate, for the treatment of
endometriosis-associated pain in young women with endometriosis.
cabergoline, with a clinical standard therapy, norethindrone acetate, for the treatment of
endometriosis-associated pain in young women with endometriosis.
Inclusion Criteria:
- Surgically confirmed endometriosis
- Age between 15-40 y, and premenopausal
- Pelvic pain score ≥3 on a Visual Analog Scaleover the last month
Exclusion Criteria:
- Use of other concurrent hormone medications (such as birth control pills)
- Impaired liver function (ALT > 2x normal) or liver disease (cirrhosis, hepatitis)
- Pregnancy
- Breast cancer
- Active thromboembolic disease
- Uncontrolled hypertension, history of cardiac valve disorder, history of fibrotic
disorders
We found this trial at
1
site
Boston, Massachusetts 02115
Principal Investigator: Amy D DiVasta, MD, MMSc
Phone: 617-355-3792
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