Noom Monitor for Binge Eating

Binge eating is a core maladaptive behavior characteristic of several forms of eating
pathology, including bulimia nervosa (BN) and binge eating disorder (BED). These chronic
conditions affect approximately 5% of the population, and cause significant psychosocial and
physical impairment. However, a number of barriers prevent the implementation of effective
treatments, including poor treatment adherence, a paucity of specialized therapists, and high
rates of drop out. The guided self-help version of cognitive-behavior therapy (CBT-GSH) is a
brief 8-session highly scalable treatment to reduce binge eating. Moreover, CBT-GSH is a
cost-effective empirically supported treatment that has been demonstrated to reduce total
health care costs.

Although CBT-GSH for BN and BED is effective, few individuals receive these treatments and
the majority of other available treatments do not meet adequate standards for care for eating
disorders. There are a number of reasons for why this is the case, but an important concern
about CBT-GSH is participant burden. The primary CBT-GSH intervention is self-monitoring, a
uniquely effective technique for reducing binge eating episodes; however, traditional
self-monitoring is time-intensive and cumbersome because of its paper-and-pencil format. In
addition, other behavioral strategies utilized in CBT-GSH (e.g., the development of regular
eating) require a high degree of participant engagement outside of session. Novel
technologies, such as those available with smartphones, offer potentially important means for
reducing participant burden in the delivery of CBT-GSH. The purpose of the proposed is to
test the primary efficacy of a novel mobile app, 'Noom Monitor' in a large population of
binge eaters relative to a well-established treatment as usual (TAU) control condition. The
investigative team developed these products via phase I study (R41-MH096435) to facilitate
delivery of a cognitive-behavior therapy version of Guided Self-Help.

The efficacy and product development aims of this proposal will be used to support the
commercial launch of Noom Monitor, a smartphone platform.

Inclusion Criteria:

- Meets for DSM-5 BN or BED criteria

- Between the ages of 18 and 50

- Males and females

- BMI greater than 18.5 and less than 40

- Medical clearance in the case of reported purging or extreme exercise

- Free of psychiatric medication for at least 2 weeks prior to study or on a stable dose
of medication for 4 weeks

- 1 year continuous enrollment in Kaiser Permanente Northwest health plan

Exclusion Criteria:

- Has undergone bariatric surgery

- Demonstrates need for higher level of care (e.g., very low weight (<18.5))

- Current comorbid substance dependence, bipolar or psychotic illness

- Current suicidal ideation

- Previously received Enhance Cognitive behavioral therapy or Cognitive behavioral
therapy-guided self help

- Previously read Overcoming Binge Eating by Christopher Fairburn

- Purging and/or laxative use more than 2x a day on average over the last month.